http://odlarmed.com All About Medicine Sun, 23 May 2010 13:06:39 +0000 http://backend.userland.com/rss092 en What is a kidney stone? A kidney stone is a hard, crystalline mineral material formed within the kidney or urinary tract. Kidney stones are a common cause of blood in the urine and often severe pain in the abdomen, flank, or groin. Kidney stones are sometimes called renal calculi. One in ... http://odlarmed.com/?p=4052 Sızanaq problemini bəslənmə nizamı, stres, siqaret, spirt kimi faktorlar tetikləyə bilər. Bu səbəblə bunlardan uzaq durun. Tətbiq edəcəyiniz düstura gəlincə: Bir çay qaşığı düyü nişastası, yarım çay qaşığı karbonat, bir çay qaşığı alma sirkəsini qarışdırın. Zeytunyağlı sabunla yuduğunuz yüzünüzə maskanı sürün və 20 dəqiqə gözlədin. Yuduqdan sonra bir şüşə mineral ... http://odlarmed.com/?p=4048 Acute coronary syndromes, ACS, percutaneous coronary intervention, PCI, clopidogrel, prasugrel, CYP2C19 Overview Warfarin (Coumadin) is the most commonly used vitamin K antagonist. It has demonstrated effectiveness for the primary and secondary prevention of venous thromboembolism, for the prevention of systemic embolism in patients with prosthetic heart valves or atrial fibrillation, as an ... http://odlarmed.com/?p=4043 Clopidogrel Dosing and CYP2C19 Overview Clopidogrel (Plavix), a second-generation thienopyridine that inhibits platelet aggregation, is a mainstay, along with aspirin, in the management of patients with coronary artery disease, with acute coronary syndromes (ACS), and/or after percutaneous coronary interventions (PCI). Yet, a significant proportion of patients remains at risk for subsequent ... http://odlarmed.com/?p=4040 Lung Cancer and EGFR Overview A substantial percentage of lung cancers express cell surface epidermal growth factor receptors (EGFRs). As activation of these cell surface receptors has been shown in experimental systems to result in the growth and progression of the malignancy, there have been considerable pre-clinical and clinical research efforts ... http://odlarmed.com/?p=4037 Fluorouracil Toxicity and DPYD Overview 5-Fluorouracil (5FU) is a fluorinated pyrimidine analogue commonly used in combination chemotherapy regimens for patients with breast, colorectal, lung, and other malignancies. Dihydropyrimidine dehydrogenase (DPD), an enzyme encoded by the DPYD gene, is the rate-limiting step in pyrimidine catabolism and deactivates more than 80% of standard ... http://odlarmed.com/?p=4033 Colorectal Cancer and KRAS Overview One actively investigated approach in the management of advanced and metastatic colorectal cancer (CRC) has been the delivery of agents whose primary purpose is to interfere with the biological activity of the epidermal growth factor receptor (EGFR). However, it is well-recognized that only a subset of patients ... http://odlarmed.com/?p=4030 Chronic Myeloid Leukemia and BCR-ABL Overview Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is one of the few cancers that is known to caused by a single, specific genetic mutation in more than 90% of cases. The transformation to CML is caused by a reciprocal translocation of the BCR ... http://odlarmed.com/?p=4027 Breast Cancer and HER2 Overview Approximately 30% of malignant breast cancers demonstrate overamplification of the human epidermal receptor type 2 (HER2) gene, resulting in  an overexpression of the HER2 receptor, a transmembrane tyrosine kinase receptor within the epidermal growth factor receptor (EGFR) family. Activation of this class of cellular receptors is ... http://odlarmed.com/?p=4024 HEMOFİLİYA Qanda Faktor 8 və faktor 9 adlı iki zülal olur. Hemofiliya vəziyyətində bunlar qanda əskikdir. Bu iki zülalın qanda olmaması, miqdarının azalması ya da funksiyasının pozulması vəziyyətində, qan laxtalana bilməz və qanamağa səbəb olar. İlk olaraq 1920-ci ildə təyin olunan hemofiliya, irsi faktorlara (soyaçekim) bağlı olaraq inkişaf edən ciddi qanamalara yolaçan ... http://odlarmed.com/?p=4019